Who are the only people who can prescribe Schedule 2 substances?

• A. Dentists
• B. Nurses with delegation
• C. Pharmacists
• D. Physicians

Answer: (D)

Schedule II substances are tightly controlled because they have a high potential for abuse and dependence, so the authority to prescribe them is reserved for physicians. A physician has the medical training to determine medical necessity, monitor patient safety, and manage risks associated with powerful opioids and similar drugs. Because of that oversight, only a physician can independently issue a Schedule II prescription in this context. Other professionals may administer or dispense medications under a physician’s order or prescribe lower-strength or other schedules under their own delegated authority, but they do not have independent authority to prescribe Schedule II drugs. If you’re in a setting where advanced practice clinicians or other prescribers exist, check your state rules, but for this item the physician is the correct prescriber.